Oncology

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CAR T-cell therapy effective, but serious toxicities and high cost are considerations

KEY POINT

A single infusion of tisagenlecleucel (Kymriah—Novartis) administered to pediatric patients and young adults with B-cell acute lymphoblastic leukemia (ALL) resulted in a highly durable remission rate, according to results of a Phase II study published in the New England Journal of Medicine.