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Herbal Interactions: Concern Grows

KEY POINT

From the medical literature to television news programs, big concerns have arisen about interactions between traditional medications and herbal drugs. In particular, new information last month about St. John’s wort prompted an FDA advisory for prescribers, pharmacists, and patients (www.fda.gov).

SOURCES

Piscatelli SC et al. Indinavir concentrations and St. John’s wort. Lancet. 2000;355:547.

Ruschitzka F et al. Acute heart transplant rejection due to St. John’s wort. Lancet. 2000;355:548.

Various authors. Safety of St. John’s wort (Hypericum perforatum). Lancet. 2000;355:575 ff.