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Infectious Diseases

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April 24, 2018

Trimethoprim is associated with negative renal outcomes in older adults

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Use of trimethoprim for management of urinary tract infections (UTIs) in older adults was associated with a higher risk of acute kidney injury (AKI) and hyperkalemia compared with other...
April 16, 2018

Updated Clostridium difficile guidelines released

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Updated guidelines for management of Clostridium difficile infections in adults and children, published in Clinical Infectious Diseases, focus on diagnosis, infection prevention...
March 13, 2018

PPIs decrease the effectiveness of hepatitis C antivirals

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Sustained virologic responses (SVRs) were lower in patients with hepatitis C taking direct-acting antivirals with proton pump inhibitors (PPIs) compared with those not receiving PPIs, according to...
March 6, 2018

Surgical site infection risk increased in patients who reported a penicillin allergy

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Patients undergoing a variety of surgical procedures who reported a penicillin allergy were at a 50% increased odds of having a surgical site infection, according to results of a retrospective...
February 12, 2018

Perioperative timing of infliximab did not alter the risk of serious infection

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The risk of serious infections within 30 days or 1 year after elective hip or knee surgery was similar in patients who stopped infliximab (Remicade—Janssen) within 2 to 4 weeks of surgery compared...

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APhA DrugInfoLine (ISSN 2162-3015) is a weekly publication of, and is owned and copyrighted by the American Pharmacists Association, the national professional society of pharmacists. Materials in APhA DrugInfoLine do not neccessarily represent the policy, recommendations, or endorsement of APhA. The publisher, authors, editors, reviewers, and contributors have taken care to ensure that the information contained in APhA DrugInfoLine is accurate and current; however, they shall have no ability to any person or entity with regard to claims, losses, or damage caused or alleged to be caused, directly or indirectly by use of any information contained in the publication. All decisions about drug therapy must be based on independent judgement of the clinician.