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Elderly Patients with Heart Failure: ACE Inhibitors Preferred over Angiotensin II Blockers

KEY POINT

Recently completed studies of elderly patients with congestive heart failure show no difference in effectiveness between the ACE inhibitor captopril (Capoten—Bristol-Myers Squibb) and the angiotensin II antagonist losartan (Cozaar—Merck). Unless patients are intolerant of the side effects of ACE inhibitors, these established agents remain the treatment of first choice.

SOURCES

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Davies MK et al. ABC of heart failure. Management: diuretics, ACE inhibitors, and nitrates. BMJ. 2000;320:428 ff.

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