Drug Interactions Corner

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Raloxifene Interference with Levothyroxine Absorption

KEY POINT

Raloxifene (Evista—Lilly) likely decreases the absorption of levothyroxine in patients taking both medications, and monitoring of thyroid function is needed to ensure adequate treatment.

SOURCES

Siraj ES et al. Raloxifene causing malabsorption of levothyroxine. Arch Intern Med. 2003;163:1367–70.