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Azithromycin use improves outcomes in patients with persistent asthma

KEY POINT

Use of azithromycin 500 mg three times per week as an add-on therapy to long-term controller medications in patients with uncontrolled persistent asthma resulted in fewer asthma exacerbations and improved asthma-related quality of life compared with placebo according to results of a study published in Lancet.

SOURCES

Gibson PG, et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. Lancet. 2017;[Epub ahead of print]. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31281-3/fulltext

Brusselle G, et al. Azithromycin in uncontrolled asthma. Lancet. 2017;[Epub ahead of print]. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31547-7/fulltext