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Inhaled Corticosteroids in Asthma: Less Is Better

KEY POINT

While too preliminary to be incorporated into daily practice, two recently published studies are challenging the status quo when it comes to identification of optimal inhaled corticosteroid strategies in patients with mild or moderate asthma.

SOURCES

Boushey HA et al. Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005;352:1519–28.

Fabbri LM. Does mild persistent asthma require regular treatment [editorial]? N Engl J Med. 2005;352:1589–91.

Smith AD et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med. 2005;352:2163–73.

Deykin A. Targeting biologic markers in asthma—is exhaled nitric oxide the bull’s-eye [editorial]? N Engl J Med. 2005;352:2233–35.