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Antihypertensives and new-onset diabetes: New supportive findings


An analysis of the three cohort studies, Nurses’ Health Study (NHS) I and II and the Health Professionals Follow up Study (HPFS), confirms what has long been suspected: Certain antihypertensive medications can significantly increase patients’ risk of developing new-onset diabetes. Study data reveal that the relative risk of developing asymptomatic and symptomatic new-onset diabetes for hypertensive patients taking a thiazide diuretic or beta-blocker ranges from 20% to 45% and 20% to 32%, respectively, depending on the patient’s gender and age group.


Taylor EN et al. Antihypertensive medications and the risk of incident type 2 diabetes. Diabetes Care. 2006;29:1065–70.

Saratidis P et al. Antihypertensive therapy and the risk of new-onset diabetes. Diabetes Care. 2006;29:1167–9.