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Dietary Fats: Effects on Insulin Resistance

KEY POINT

In certain types of patients, insulin resistance may result from consumption of dietary fats, perhaps even a specific isomer of linoleic acid.

SOURCES

Lovejoy JC et al. Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults. Diabetes Care. 2002;15:1283–8.

Risérus U et al. Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care. 2002;15:1516–21.