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Individualizing diabetes therapy in high-risk patients

KEY POINT

To maximize treatment benefits while minimizing adverse outcomes in high-risk patients with type 2 diabetes, authors of a recent analysis of the ACCORD (Action to Control Cardiovascular Risk in Diabetes) study and other cardiovascular trial data suggest that clinicians individualize A1C goals before treatment based on patient risk factors and during treatment if patients do not respond to initial therapy. Therapy should be personalized in patients unable to sustain goal A1C.