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Sibutramine Improves Metabolic Control in Patients with Diabetes, Obesity

KEY POINT

In obese patients with type 2 diabetes, increased weight loss and an accompanying improvement in metabolic control can result from treatment with sibutramine (Meridia—Abbott) in combination with metformin.

SOURCES

McNulty SJ et al. A randomized trial of sibutramine in the management of obese type 2 diabetic patients treated with metformin. Diabetes Care. 2003;26:125–31. 

Peeters A et al. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med. 2003;138:24–32.