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Simvastatin, Acarbose: Stopping Problems Before They Start

KEY POINT

Two recently published studies emphasize the importance of strategies for avoiding cardiovascular disease in patients with diabetes and even in those in the prediabetes stage.

SOURCES

Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005–16. 

Lindholm LH. Major benefits from cholesterol-lowering in patients with diabetes [commentary]. Lancet. 2003;361:2000–1. 

Chiasson J-L et al. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: The STOP-NIDDM Trial. JAMA. 2003;290:486–94.