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Four-drug regimen for H. pylori better than standard three-drugs


Data from 135 patients with treatment-naive Helicobacter pylori infections showed that a four-drug regimen of levofloxacin (Levaquin—Ortho-McNeil-Janssen), omeprazole, nitazoxanide (Alinia—Romark), and doxycycline (LOAD) given for 7 or 10 days eradicated the bacterium in 95% of patients compared with an 81% eradication rate for the standard 10-day three-drug regimen of lansoprazole (Prevacid—Takeda), amoxicillin, and clarithromycin (LAC).