In patients with diarrhea-predominant irritable bowel syndrome (IBS-D), ondansetron administered for 5 weeks significantly improved stool consistency, frequency, and urgency compared with placebo in a recent trial.
Garsed K et al. A randomized trial of ondansetron for the treatment of irritable bowel syndrome with diarrhea. Gut. 2013;[Epub ahead of print].
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