Infectious Diseases

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Chronic sinusitis: Which treatments work best?


Evidence supports treating chronic sinusitis in adults with daily topical corticosteroids and adjunctive daily saline irrigations, with additional therapies preferred for those with nasal polyps (i.e., short-course of systemic corticosteroids, 3 wk-course of doxycycline, or leukotriene antagonist) and those without polyps (i.e., prolonged course of antibiotics), according to results of a large systematic review.


Rudmik L et al. Medical therapies for adult chronic sinusitis: A systematic review. JAMA. 2015; 314:926–39.  

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