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“Best treatment” for early-stage prostate cancer not identified; adverse effects from all


A review prepared for the Agency for Healthcare Research and Quality and recently published in the Annals of Internal Medicine found that insufficient data existed comparing the efficacy and/or safety of available localized prostate cancer treatments (e.g., watchful waiting, radical prostatectomy, brachytherapy, and androgen deprivation).


Wilt TJ et al. Systematic review: comparative effectiveness and harms of treatments for clinically localized prostate cancer. Ann Intern Med 2008; [published online February 5, 2008].