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Observation is an acceptable alternative to surgery for men with localized prostate cancer


After nearly 20 years of follow-up, men with localized prostate cancer who underwent surgery had no significant benefits in all-cause or prostate-related mortality compared with men who chose observation of their disease, according to results of the landmark PIVOT (Prostate Cancer Intervention versus Observation Trial) trial published in the New England Journal of Medicine.


Wilt TJ, et al. Follow-up of prostatectomy versus observation for early prostate cancer. N Engl J Med. 2017;377:132–42.