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Effective treatment for early-stage COPD


Use of once-daily tiotropium (Spiriva—Boehringer Ingelheim) in patients with mild to moderate COPD resulted in higher lung function measures (i.e., forced expiratory volume in 1 second [FEV1]) and less annual decline in lung function compared with placebo, according to results of a study published in the New England Journal of Medicine.


Zhou Y, et al. Tiotropium in early-stage chronic obstructive pulmonary disease. N Engl J Med. 2017;377(10):923–35.

Ko FWS, et al. Drug treatment for early-stage COPD. N Engl J Med. 2017;377(10):988–9.

Woodruff P, et al. Clinical significance of symptoms in smokers with preserved pulmonary function. N Engl J Med. 2016;374(19):1811–21.

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