Medication Monitor



Generic Name (Trade Name—Company)
Notes
January 1, 2011

Acetaminophen injection

(Ofirmev—Cadence)
Injectable acetaminophen approved for children and adults

Uses:

Treatment of mild to moderate pain and moderate to severe pain with adjunctive opioid analgesics and for the reduction of fever in patients 2 years and older

This is the first and only I.V. form of acetaminophen approved by FDA. It can be given as a single dose or as repeated doses. The recommended dose for adults and adolescents weighing 50 kg or more is 1,000 mg every 6 hours or 650 mg every 4 hours to a maximum of 4,000 mg/d. For adults and adolescents weighing less than 50 kg, and for children 2–12 years old, the recommended dose is 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours to a maximum of 75 mg/kg/d. This new formulation will be marketed in 100-mL glass vials containing 1,000 mg of acetaminophen.